SCHEMBL9612864

SCHEMBL9612864

Cc1ccc(-c2cccc3c(-c4c5ccccc5c(-c5ccc(-c6ccc(-c7ccc8ccccc8c7)nc6)cc5)c5ccccc45)cccc23)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTRC Q99895 1/20 0.40
ALDH1A1 P00352 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ENPP1 P22413 2/20 0.37
PIM1 P11309 1/20 0.37
MET P08581 1/20 0.36
ENPP3 O14638 1/20 0.36
PARP1 P09874 1/20 0.36
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
HSD17B1 P14061 1/20 0.35
HSD17B2 P37059 1/20 0.35
RAC1 P63000 2/20 0.34
FLT3 P36888 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9612994 0.87 ENPP1 (0.38) ALDH1A1CYP3A4HPGDSMN1; SMN2ENPP1
SCHEMBL9612997 0.83 COMT (0.39) ALDH1A1CYP3A4HPGDSMN1; SMN2CYP11B1
SCHEMBL10032784 0.83 CCR1 (0.43) CTRCALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL10032752 0.82 CYP3A4 (0.40) CTRCALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL10017052 0.82 CYP17A1 (0.40) ALDH1A1SMN1; SMN2PIM1CYP11B1CYP11B2
SCHEMBL26567152 0.81 CTRC (0.50) CTRCALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL19170433 0.81 CYP11B1 (0.42) ALDH1A1CYP1A2CYP2C9HPGDSMN1; SMN2
SCHEMBL9613086 0.81 ENPP1 (0.41) ALDH1A1HPGDENPP1ENPP3CYP11B1
SCHEMBL9613154 0.81 CYP11B1 (0.38) CYP1A2SMN1; SMN2CYP11B1CYP11B2MAOB
SCHEMBL12436956 0.80 CYP1A1 (0.42) ALDH1A1CYP1A2CYP2C9HPGDPIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012070535-A1 ELECTRON TRANSPORT MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME JNC株式会社 (JP) 2012-05-31 WO disclosed