SCHEMBL9613086

SCHEMBL9613086

Cc1ccc(-c2ccc(-c3c4ccccc4c(-c4cccc(-c5ccc(-c6cccc7ccccc67)nc5)c4)c4ccccc34)c3ccccc23)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP1 P22413 3/20 0.41
ENPP3 O14638 1/20 0.41
CYP11B1 P15538 3/20 0.39
CYP11B2 P19099 3/20 0.39
FLT3 P36888 1/20 0.38
CA12 O43570 4/20 0.38
CA9 Q16790 4/20 0.38
CA1 P00915 3/20 0.38
CA2 P00918 3/20 0.38
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
HSD17B1 P14061 1/20 0.35
HSD17B2 P37059 1/20 0.35
TNF P01375 1/20 0.35
DHFR P00374 1/20 0.34
COMT P21964 1/20 0.34
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
GPR84 Q9NQS5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9613088 0.93 CA12 (0.40) ENPP1ENPP3CYP11B1CYP11B2CA12
SCHEMBL21249210 0.84 CA12 (0.40) ENPP1ENPP3CYP11B1CYP11B2CA12
SCHEMBL9613030 0.83 COMT (0.41) ENPP1FLT3KDM4EALDH1A1COMT
SCHEMBL12435751 0.83 CA12 (0.41) CYP11B1CYP11B2CA12CA9CA1
SCHEMBL26564751 0.82 CYP11B1 (0.44) ENPP1ENPP3CYP11B1CYP11B2FLT3
SCHEMBL12435750 0.81 CYP11B1 (0.45) ENPP1ENPP3CYP11B1CYP11B2CA12
SCHEMBL21249206 0.81 CA12 (0.40) ENPP1ENPP3CYP11B1CYP11B2CA12
SCHEMBL26567174 0.81 CYP11B1 (0.43) ENPP1ENPP3CYP11B1CYP11B2FLT3
SCHEMBL9612994 0.81 ENPP1 (0.38) ENPP1ENPP3CYP11B1CYP11B2KDM4E
SCHEMBL9612864 0.81 CTRC (0.40) ENPP1ENPP3CYP11B1CYP11B2FLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012070535-A1 ELECTRON TRANSPORT MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME JNC株式会社 (JP) 2012-05-31 WO disclosed