SCHEMBL9612974

SCHEMBL9612974

CCc1ccc(-c2c3ccccc3c(-c3ccc(-c4cccnc4-c4cccc5ccccc45)cc3)c3ccccc23)c2ccccc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK11 Q15759 1/20 0.37
MAPK14 Q16539 1/20 0.37
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
BCHE P06276 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA7 P36544 1/20 0.36
HTR2C P28335 2/20 0.35
PPARG P37231 2/20 0.35
PPARA Q07869 2/20 0.35
ENPP1 P22413 2/20 0.35
TGFBR1 P36897 2/20 0.34
KDM4E B2RXH2 2/20 0.34
ENPP3 O14638 1/20 0.34
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9612804 0.87 PTGS2 (0.50) PTGS1PTGS2ALDH1A1HSD17B10DHODH
SCHEMBL9613128 0.85 TNF (0.43) MAPK11MAPK14PTGS1PTGS2BCHE
SCHEMBL9612977 0.82 DHODH (0.46) PTGS1PTGS2DHODHCA12CA1
SCHEMBL9613004 0.80 HTR2C (0.40) MAPK11MAPK14CHRNB4CHRNA3CHRNA7
SCHEMBL9613137 0.77 BCHE (0.42) MAPK11MAPK14BCHETGFBR1KDM4E
SCHEMBL9612930 0.76 DHODH (0.50) CHRNB4CHRNA3CHRNA7ENPP1KDM4E
SCHEMBL2790909 0.75 TNF (0.40) PTGS1PTGS2BCHEENPP1TGFBR1
SCHEMBL14525852 0.75 BCHE (0.43) MAPK11MAPK14BCHEENPP1TGFBR1
SCHEMBL10016888 0.75 CYP1A2 (0.38) PTGS1PTGS2TGFBR1ALDH1A1MAPT
SCHEMBL9613127 0.73 COMT (0.34) MAPK11MAPK14PTGS1PTGS2BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012070535-A1 ELECTRON TRANSPORT MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME JNC株式会社 (JP) 2012-05-31 WO disclosed