Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 3/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.64 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | CDC7 | O00311 | 1/20 | 0.57 |
| ▸ | EEF2K | O00418 | 1/20 | 0.57 |
| ▸ | PLK4 | O00444 | 1/20 | 0.57 |
| ▸ | AURKA | O14965 | 1/20 | 0.57 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.57 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.57 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.57 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.57 |
| ▸ | PIM1 | P11309 | 1/20 | 0.57 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.57 |
| ▸ | CDK2 | P24941 | 1/20 | 0.57 |
| ▸ | AKT1 | P31749 | 1/20 | 0.57 |
| ▸ | AKT2 | P31751 | 1/20 | 0.57 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9613356 | 0.91 | PTPN1 (0.60) | PTPN2PTPN1PTPN5ALDH1A1LMNA | |
| SCHEMBL1459765 | 0.77 | AURKA (0.68) | AURKAAURKB | |
| SCHEMBL5704502 | 0.76 | ALDH1A1 (0.64) | PTPN2PTPN1PTPN5ALDH1A1LMNA | |
| SCHEMBL4589934 | 0.76 | PTPN2 (0.57) | PTPN2PTPN1PTPN5ALDH1A1LMNA | |
| SCHEMBL9175506 | 0.75 | SMN1; SMN2 (0.76) | ALDH1A1LMNASMN1; SMN2AKT1KDM4E | |
| SCHEMBL6764847 | 0.74 | PIK3CD (0.68) | PTPN2PTPN1PTPN5ALDH1A1LMNA | |
| SCHEMBL12595573 | 0.74 | ALDH1A1 (0.79) | ALDH1A1LMNASMN1; SMN2AKT1AKT2 | |
| SCHEMBL12595616 | 0.74 | ALDH1A1 (0.79) | ALDH1A1LMNASMN1; SMN2AKT1AKT2 | |
| SCHEMBL18083001 | 0.74 | ALDH1A1 (0.93) | ALDH1A1LMNASMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL3886334 | 0.74 | PTPRC (0.61) | PTPN2PTPN1PTPN5ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012071414-A2 | QUINOXALINE COMPOUNDS AND USES THEREOF | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2012-05-31 | — | — | WO | disclosed |