Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 7/20 | 0.60 |
| ▸ | PTPN5 | P54829 | 7/20 | 0.60 |
| ▸ | PTPN2 | P17706 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HSPD1 | P10809 | 3/20 | 0.55 |
| ▸ | HSPE1 | P61604 | 3/20 | 0.55 |
| ▸ | CDC7 | O00311 | 1/20 | 0.53 |
| ▸ | EEF2K | O00418 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9613293 | 0.91 | PTPN2 (0.64) | PTPN1PTPN5PTPN2ALDH1A1MAPT | |
| SCHEMBL8541050 | 0.76 | PIK3CD (0.57) | PTPN1PTPN5PTPN2ALDH1A1MAPT | |
| SCHEMBL2243342 | 0.75 | PTPN1 (1.00) | PTPN1PTPN5PTPN2ALDH1A1MAPT | |
| SCHEMBL6986051 | 0.73 | LMNA (0.65) | PTPN1PTPN5PTPN2ALDH1A1MAPT | |
| SCHEMBL6985862 | 0.73 | ALDH1A1 (0.78) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13480185 | 0.73 | KMT2A (0.77) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1461030 | 0.73 | AURKA (0.67) | AURKAAURKB | |
| SCHEMBL13868900 | 0.73 | MAP2K4 (0.68) | ALDH1A1AURKAAURKB | |
| SCHEMBL810795 | 0.73 | KMT2A (0.91) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL2614387 | 0.73 | SMN1; SMN2 (1.00) | ALDH1A1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012071414-A2 | QUINOXALINE COMPOUNDS AND USES THEREOF | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2012-05-31 | — | — | WO | disclosed |