Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 12/20 | 0.53 |
| ▸ | HSPA1A | P0DMV8 | 11/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | GAPDH | P04406 | 7/20 | 0.52 |
| ▸ | POLB | P06746 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | BLM | P54132 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.52 |
| ▸ | CDC25B | P30305 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MASP2 | O00187 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | CD44 | P16070 | 2/20 | 0.52 |
| ▸ | MSN | P26038 | 2/20 | 0.52 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9613389 | 0.86 | POLB (0.57) | PTPN7HSPA1ATDP1GAPDHPOLB | |
| SCHEMBL15357609 | 0.83 | RPS6KB2 (0.42) | PTPN7HSPA1ATDP1GAPDHPOLB | |
| SCHEMBL31492743 | 0.70 | PTPN7 (1.00) | PTPN7HSPA1ATDP1GAPDHPOLB | |
| SCHEMBL26098723 | 0.70 | PTPN7 (1.00) | PTPN7HSPA1ATDP1GAPDHPOLB | |
| SCHEMBL3610631 | 0.69 | CDC25B (1.00) | PTPN7HSPA1ATDP1GAPDHPOLB | |
| SCHEMBL2808722 | 0.69 | PTPN7 (1.00) | PTPN7HSPA1ATDP1GAPDHPOLB | |
| SCHEMBL13186581 | 0.69 | PTPN7 (0.73) | PTPN7HSPA1ATDP1GAPDHPOLB | |
| SCHEMBL2116528 | 0.69 | PTPN7 (1.00) | PTPN7HSPA1ATDP1GAPDHPOLB | |
| SCHEMBL16706087 | 0.69 | PTPN7 (1.00) | PTPN7HSPA1ATDP1GAPDHPOLB | |
| SCHEMBL16706084 | 0.67 | POLB (1.00) | PTPN7HSPA1ATDP1GAPDHPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012071414-A2 | QUINOXALINE COMPOUNDS AND USES THEREOF | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2012-05-31 | — | — | WO | disclosed |