Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.61 |
| ▸ | PPARA | Q07869 | 17/20 | 0.61 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9614353 | 0.92 | PPARG (0.59) | PPARGPPARA | |
| SCHEMBL9613891 | 0.88 | PPARA (0.68) | PPARGPPARA | |
| SCHEMBL9613928 | 0.88 | PPARG (0.60) | PPARGPPARAPTGESALOX5 | |
| SCHEMBL9614258 | 0.81 | PPARA (0.65) | PPARGPPARA | |
| SCHEMBL9450979 | 0.80 | ALDH1A1 (0.41) | PPARGPPARA | |
| SCHEMBL10419468 | 0.78 | PPARG (0.67) | PPARGPPARAPTGESALOX5 | |
| SCHEMBL9613951 | 0.77 | PPARA (0.67) | PPARGPPARA | |
| SCHEMBL9614318 | 0.76 | PPARG (0.59) | PPARGPPARAPTGESALOX5 | |
| SCHEMBL17724499 | 0.75 | PPARG (0.60) | PPARGPPARA | |
| SCHEMBL9614069 | 0.74 | MMP9 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145611-A | Diabetes | BOEHRINGER MANNHEIM GMBH (DE) | 1992-09-08 | — | — | US | disclosed |
| EP-0279162-B1 | CARBONIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1991-06-19 | — | — | EP | disclosed |
| EP-0279162-A1 | Carbonic acid derivatives, process for their preparation and pharmaceuticals containing them | Roche Diagnostics GmbH (DE) | 1988-08-24 | — | — | EP | disclosed |