Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.50 |
| ▸ | PPARA | Q07869 | 6/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.50 |
| ▸ | PTGES | O14684 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9614194 | 0.89 | PPARG (0.53) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9614074 | 0.85 | PPARG (0.64) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL10419188 | 0.83 | PPARG (0.52) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9695329 | 0.83 | PPARG (0.52) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9614072 | 0.82 | PPARG (0.55) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9613996 | 0.82 | PPARG (0.46) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9613992 | 0.82 | PPARA (0.44) | PPARGPPARACYP2C9CYP2C19HSD17B10 | |
| SCHEMBL9613946 | 0.80 | PPARG (0.47) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9613950 | 0.80 | PPARG (0.47) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9614197 | 0.78 | PPARG (0.71) | PPARGPPARAALOX5PTGESALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145611-A | Diabetes | BOEHRINGER MANNHEIM GMBH (DE) | 1992-09-08 | — | — | US | disclosed |