Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.44 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.44 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.44 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9614107 | 1.00 | PPARA (0.48) | PPARAPPARGPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL9858450 | 1.00 | PPARA (0.48) | PPARAPPARGPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL9614023 | 0.96 | PPARA (0.47) | PPARAPPARGPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL9614046 | 0.95 | PPARA (0.48) | PPARAPPARGPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL9613974 | 0.92 | TRPA1 (0.48) | TRPA1MAPTRXFP1TRPV1HDAC1 | |
| SCHEMBL10420392 | 0.92 | TRPA1 (0.48) | TRPA1MAPTRXFP1TRPV1HDAC1 | |
| SCHEMBL10420482 | 0.91 | PPARA (0.47) | PPARAPPARGPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL9613829 | 0.90 | KMT2A (0.45) | PPARAPPARGALDH1A1GAAMEN1 | |
| SCHEMBL9614242 | 0.87 | TDP1 (0.43) | PLAAT3PLAAT5PLAAT2PLAAT4TRPA1 | |
| SCHEMBL27272794 | 0.87 | TRPA1 (0.42) | TRPA1MAPTRXFP1TRPV1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1018548-B | CARBOXYLIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1992-10-07 | — | — | CN | disclosed |
| US-5145611-A | Diabetes | BOEHRINGER MANNHEIM GMBH (DE) | 1992-09-08 | — | — | US | disclosed |
| EP-0279162-B1 | CARBONIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1991-06-19 | — | — | EP | disclosed |
| EP-0279162-A1 | Carbonic acid derivatives, process for their preparation and pharmaceuticals containing them | Roche Diagnostics GmbH (DE) | 1988-08-24 | — | — | EP | disclosed |
| CN-88100219-A | New carboxylic acid derivative and preparation technology thereof and the medicinal compositions that contains these derivatives | — | 1988-07-27 | — | — | CN | disclosed |