Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 6/20 | 0.44 |
| ▸ | ADRB1 known ✓ | P08588 | 6/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21989 | 0.93 | THRA (0.54) | THRATHRBPPARALIPGALOX5 | |
| SCHEMBL382121 | 0.93 | THRA (0.54) | THRATHRBPPARALIPGALOX5 | |
| SCHEMBL28552517 | 0.93 | THRA (0.54) | THRATHRBPPARALIPGALOX5 | |
| Ammonia Solution, Strong SCHEMBL11585182 | 0.91 | THRA (0.52) | THRATHRBPPARALIPGALOX5 | |
| Phosphoric Acid SCHEMBL1347353 | 0.89 | THRA (0.51) | THRATHRBPPARALIPGALOX5 | |
| SCHEMBL10481827 | 0.87 | THRA (0.46) | THRATHRBPPARALIPGALOX5 | |
| Sulfuric Acid SCHEMBL11441986 | 0.84 | THRA (0.57) | THRATHRBPPARALIPGALOX5 | |
| Sulfuric Acid SCHEMBL29898210 | 0.84 | THRA (0.57) | THRATHRBPPARALIPGALOX5 | |
| Sulfuric Acid SCHEMBL284011 | 0.84 | THRA (0.57) | THRATHRBPPARALIPGALOX5 | |
| Sulfuric Acid SCHEMBL1712538 | 0.84 | THRA (0.57) | THRATHRBPPARALIPGALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0189950-B1 | CEMENT COMPOSITION FOR CEMENTING OF WELLS ENABLING GAS CHANNELLING IN THE CEMENTED ANNULUS TO BE INHIBITED BY RIGHT-ANGLE SETTING | PUMPTECH N.V. (BE) | 1989-08-23 | — | — | EP | claimed |
| EP-0378544-A4 | GERMICIDAL COMPOSITION | — | 1992-05-20 | — | — | EP | disclosed |
| EP-0378544-A1 | GERMICIDAL COMPOSITION | MDT CORPORATION (US) | 1990-07-25 | — | — | EP | disclosed |
| US-4867897-A | NONYLPHENOLPOLYOXYETHYLENE GLYCOL SULFATE | MDT CORPORATION (US) | 1989-09-19 | — | — | US | disclosed |
| WO-1989000857-A1 | GERMICIDAL COMPOSITION | MDT CORPORATION (US) | 1989-02-09 | — | — | WO | disclosed |