Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | TP53 | P04637 | 7/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | GPX4 | P36969 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8357455 | 0.91 | TP53 (0.53) | ALDH1A1TP53TDP1CYP3A4MEN1 | |
| SCHEMBL29349823 | 0.91 | TP53 (0.74) | ALDH1A1TP53TDP1CYP3A4MEN1 | |
| SCHEMBL65705 | 0.91 | TP53 (0.74) | ALDH1A1TP53TDP1CYP3A4MEN1 | |
| SCHEMBL10789800 | 0.87 | TP53 (0.59) | ALDH1A1TP53TDP1CYP3A4MEN1 | |
| SCHEMBL9292633 | 0.87 | ALDH1A1 (0.50) | ALDH1A1TP53TDP1CYP3A4MEN1 | |
| SCHEMBL11795171 | 0.87 | TP53 (0.44) | ALDH1A1TP53TDP1CYP3A4MEN1 | |
| SCHEMBL10625773 | 0.86 | ALDH1A1 (0.49) | ALDH1A1TP53TDP1CYP3A4MEN1 | |
| SCHEMBL9215840 | 0.86 | ALDH1A1 (0.50) | ALDH1A1TP53TDP1CYP3A4MEN1 | |
| SCHEMBL9614344 | 0.85 | TP53 (0.53) | ALDH1A1TP53TDP1CYP3A4MEN1 | |
| SCHEMBL11381219 | 0.84 | TDP1 (0.47) | ALDH1A1TP53TDP1CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4256481-A | Selective herbicide compositions | NITROKEMIA IPARTELEPEK (HU) | 1981-03-17 | — | — | US | claimed |
| US-5155272-A | Process for the production of haloacylamides | MONSANTO COMPANY (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0096657-B1 | 2-PHENYL-2-NAPHTHYL AND 2-HETEROCYCLIC PYRIMIDINES AS ANTIDOTES FOR PROTECTING CULTURED PLANTS BEFORE PHYTOTOXIC DAMAGES CAUSED BY HERBICIDES | CIBA-GEIGY AG (CH) | 1989-04-05 | — | — | EP | disclosed |
| US-4698091-A | 2-phenylpyrimidines, 2-naphthylpyrimidines and 2-heterocyclylpyrimidines as safeners for protecting cultivated plant against phytotoxic damage caused by herbicides | CIBA-GEIGY CORPORATION (US) | 1987-10-06 | — | — | US | disclosed |
| EP-0096657-A2 | 2-Phenyl-2-naphthyl and 2-heterocyclic pyrimidines as antidotes for protecting cultured plants before phytotoxic damages caused by herbicides | CIBA-GEIGY AG (CH) | 1983-12-21 | — | — | EP | disclosed |
| US-4373945-A | Herbicidal agents based on acetanilides | BASF AKTIENGESELLSCHAFT (DE) | 1983-02-15 | — | — | US | disclosed |
| EP-0007575-B1 | HERBICIDAL COMPOSITIONS BASED ON ACETANILIDES AND THEIR USE IN COMBATING UNDESIRED PLANT GROWTH | BASF Aktiengesellschaft (DE) | 1981-12-23 | — | — | EP | disclosed |
| US-4300945-A | Synergistic herbicidal compositions | STAUFFER CHEMICAL COMPANY (US) | 1981-11-17 | — | — | US | disclosed |
| US-4256481-A | Selective herbicide compositions | NITROKEMIA IPARTELEPEK (HU) | 1981-03-17 | — | — | US | disclosed |
| EP-0007575-A1 | Herbicidal compositions based on acetanilides and their use in combating undesired plant growth | BASF Aktiengesellschaft (DE) | 1980-02-06 | — | — | EP | disclosed |