Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.30 |
| ▸ | LMNA | P02545 | 3/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16446965 | 1.00 | HPGD (0.33) | HPGDPOLBCTNNB1WNT3ACHRM2 | |
| SCHEMBL11104413 | 1.00 | HPGD (0.33) | HPGDPOLBCTNNB1WNT3ACHRM2 | |
| SCHEMBL1799676 | 0.92 | TDP1 (0.33) | HPGDTDP1LMNAALDH1A1 | |
| SCHEMBL11350296 | 0.89 | P2RX7 (0.32) | SLC6A3CES2CES1GAAMEN1 | |
| SCHEMBL8044926 | 0.89 | P2RX7 (0.32) | SLC6A3CES2CES1GAAMEN1 | |
| SCHEMBL9594501 | 0.89 | P2RX7 (0.32) | SLC6A3CES2CES1GAAMEN1 | |
| SCHEMBL6142427 | 0.83 | TDP1 (0.34) | POLBCTNNB1WNT3ATDP1NPSR1 | |
| SCHEMBL1799677 | 0.78 | HPGD (0.33) | HPGDPOLBCHRM2ADRA2BDRD3 | |
| SCHEMBL6142770 | 0.78 | HPGD (0.33) | HPGDPOLBCHRM2ADRA2BDRD3 | |
| SCHEMBL2471234 | 0.78 | HPGD (0.33) | HPGDPOLBCHRM2ADRA2BDRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466773-A4 | COUMARIN DERIVATIVES FOR USE AS NUCLEOTIDE CROSSLINKING REAGENTS | — | 1992-02-05 | — | — | EP | disclosed |
| EP-0466773-A1 | COUMARIN DERIVATIVES FOR USE AS NUCLEOTIDE CROSSLINKING REAGENTS. | NAXCOR (US) | 1992-01-22 | — | — | EP | disclosed |
| WO-1990012020-A1 | COUMARIN DERIVATIVES FOR USE AS NUCLEOTIDE CROSSLINKING REAGENTS | NAXCOR (US) | 1990-10-18 | — | — | WO | disclosed |