Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9594501 | 1.00 | P2RX7 (0.32) | P2RX7PTGS2GSK3BCES2CES1 | |
| SCHEMBL11350296 | 1.00 | P2RX7 (0.32) | P2RX7PTGS2GSK3BCES2CES1 | |
| SCHEMBL16446965 | 0.89 | HPGD (0.33) | CES2CES1MEN1GAAKMT2A | |
| SCHEMBL9614440 | 0.89 | HPGD (0.33) | CES2CES1MEN1GAAKMT2A | |
| SCHEMBL11104413 | 0.89 | HPGD (0.33) | CES2CES1MEN1GAAKMT2A | |
| SCHEMBL3268947 | 0.84 | P2RX7 (0.30) | P2RX7PTGS2 | |
| SCHEMBL5971739 | 0.83 | HPGD (0.34) | P2RX7PTGS2SLC6A3 | |
| SCHEMBL1799676 | 0.82 | TDP1 (0.33) | — | |
| SCHEMBL2476289 | 0.78 | GSK3B (0.32) | P2RX7GSK3BCES2CES1MEN1 | |
| SCHEMBL2476284 | 0.78 | GSK3B (0.32) | P2RX7GSK3BCES2CES1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635517-B1 | Process for Producing 1-(2'-deoxy-beta-D-erythropentofuranosyl)-5-trifluoromethyluracil Derivatives | MITSUI CHEMICALS INC (JP) | 2000-05-17 | — | — | EP | disclosed |
| EP-0990651-A1 | Process for producing 5-trifluoromethyluracil derivatives | Mitsui Chemicals, Inc. (JP) | 2000-04-05 | — | — | EP | disclosed |
| US-5532349-A | ANTITUMOR, VIRICIDES | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0635517-A1 | Process for Producing 1-(2'-deoxy-beta-D-erythropentofuranosyl)-5-trifluoromethyluracil Derivatives | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1995-01-25 | — | — | EP | disclosed |