Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDE | P14735 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9328655 | 1.00 | IDE (0.61) | IDETSHRMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL28548771 | 0.90 | TSHR (0.61) | IDETSHRMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL18874951 | 0.79 | IDE (0.73) | IDEMAPTSMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL10025042 | 0.79 | ESR1 (0.79) | TSHRMAPTSMN1; SMN2MAPK1LMNA | |
| SCHEMBL31218179 | 0.79 | ESR1 (0.79) | TSHRMAPTSMN1; SMN2MAPK1LMNA | |
| SCHEMBL439436 | 0.77 | TSHR (0.65) | TSHRMAPTL3MBTL1MAPK1LMNA | |
| SCHEMBL7992543 | 0.77 | TSHR (0.69) | TSHRMAPTL3MBTL1MAPK1LMNA | |
| SCHEMBL453284 | 0.77 | IDE (1.00) | IDEMAPTL3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL29401042 | 0.77 | IDE (1.00) | IDEMAPTL3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL12100493 | 0.77 | IDE (1.00) | IDEMAPTL3MBTL1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0465577-A1 | CATALYZED REPORTER DEPOSITION. | DU PONT (US) | 1992-01-15 | — | — | EP | disclosed |
| WO-1990011523-A2 | CATALYZED REPORTER DEPOSITION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-10-04 | — | — | WO | disclosed |