M-Xylene

M-Xylene

SCHEMBL9614482

Cc1cc(C)c(C)cc1C.Cc1cc(C)cc(C)c1.Cc1ccc(C)c(C)c1.Cc1cccc(C)c1.Cc1cccc(C)c1C.Cc1ccccc1C

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.48
RAPGEF4 Q8WZA2 5/20 0.47
TSHR P16473 1/20 0.40
CYP1A2 P05177 4/20 0.40
CYP2C19 P33261 1/20 0.40
CYP2A6 P11509 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
ALDH1A1 P00352 4/20 0.39
TP53 P04637 3/20 0.39
MAPK1 P28482 2/20 0.39
GAA P10253 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
KMT2A Q03164 1/20 0.39
MAPT P10636 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TDP1 Q9NUW8 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL323096 0.94 RAPGEF4 (0.52) ACHERAPGEF4TSHRCYP1A2CYP2A6
SCHEMBL27535148 0.89 RAPGEF4 (0.50) ACHERAPGEF4TSHRCYP1A2CYP2A6
SCHEMBL3333544 0.89 RAPGEF4 (0.50) ACHERAPGEF4TSHRCYP1A2CYP2A6
O-Xylene SCHEMBL9100131 0.82 ACHE (0.59) ACHERAPGEF4TSHRCYP1A2CYP2C19
M-Xylene SCHEMBL4596537 0.82 ACHE (0.71) ACHERAPGEF4TSHRCYP1A2CYP2C19
O-Xylene SCHEMBL10808061 0.81 ACHE (0.55) ACHERAPGEF4TSHRCYP1A2CYP2C19
P-Xylene SCHEMBL2091251 0.80 ACHE (0.67) ACHETSHRCYP1A2CYP2C19CYP2A6
P-Xylene SCHEMBL29376029 0.80 ACHE (0.67) ACHETSHRCYP1A2CYP2C19CYP2A6
M-Xylene SCHEMBL6830915 0.80 ACHE (0.75) ACHETSHRCYP1A2CYP2C19CYP2A6
SCHEMBL692221 0.80 RAPGEF4 (0.58) ACHERAPGEF4TSHRCYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0465642-A4 NEW ZEOLITE SSZ-31 1992-11-25 EP disclosed
EP-0465642-A1 NEW ZEOLITE SSZ-31 CHEVRON U.S.A. Inc. (US) 1992-01-15 EP disclosed
WO-1991011258-A1 NEW ZEOLITE SSZ-31 CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1991-08-08 WO disclosed