Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28782183 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPTLMNANPC1RAB9A | |
| SCHEMBL7210303 | 0.81 | MAPT (0.52) | ALDH1A1MAPTLMNANPC1RAB9A | |
| SCHEMBL7210312 | 0.81 | MAPT (0.49) | ALDH1A1MAPTLMNANPC1RAB9A | |
| SCHEMBL7210307 | 0.81 | MAPT (0.49) | ALDH1A1MAPTLMNANPC1RAB9A | |
| SCHEMBL8130954 | 0.80 | MTNR1A (0.52) | ALDH1A1MAPTLMNANPC1RAB9A | |
| SCHEMBL5218396 | 0.80 | MAPT (0.50) | ALDH1A1MAPTLMNANPC1RAB9A | |
| SCHEMBL4014665 | 0.79 | CYP1A2 (0.63) | ALDH1A1MAPTLMNANPC1RAB9A | |
| SCHEMBL2436193 | 0.79 | CYP1A2 (0.63) | ALDH1A1MAPTLMNANPC1RAB9A | |
| SCHEMBL6779809 | 0.79 | MEN1 (0.52) | ALDH1A1MAPTLMNANPC1RAB9A | |
| SCHEMBL2435599 | 0.78 | PDGFRB (0.56) | ALDH1A1MAPTLMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446299-A4 | METHOD FOR SITE-SPECIFICALLY INCORPORATING UNNATURAL AMINO ACIDS INTO PROTEINS | — | 1992-05-13 | — | — | EP | disclosed |
| EP-0446299-A1 | METHOD FOR SITE-SPECIFICALLY INCORPORATING UNNATURAL AMINO ACIDS INTO PROTEINS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1991-09-18 | — | — | EP | disclosed |
| WO-1990005785-A1 | METHOD FOR SITE-SPECIFICALLY INCORPORATING UNNATURAL AMINO ACIDS INTO PROTEINS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1990-05-31 | — | — | WO | disclosed |