Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536698 | 0.86 | CA2 (0.40) | CA2GABRA1GABRB2TSHRALDH1A1 | |
| SCHEMBL9466692 | 0.85 | CA2 (0.46) | CA2GABRA1GABRB2TSHRALDH1A1 | |
| SCHEMBL304569 | 0.80 | CA2 (0.57) | CA2GABRA1GABRB2TSHRALDH1A1 | |
| SCHEMBL29913900 | 0.77 | TSHR (0.43) | CA2GABRA1GABRB2TSHRALDH1A1 | |
| SCHEMBL672576 | 0.77 | TSHR (0.43) | CA2GABRA1GABRB2TSHRALDH1A1 | |
| SCHEMBL14347039 | 0.76 | CA2 (0.40) | CA2GABRA1GABRB2TSHRALDH1A1 | |
| SCHEMBL8225343 | 0.74 | CA2 (0.44) | CA2GABRA1GABRB2TSHRALDH1A1 | |
| SCHEMBL11572403 | 0.74 | CA2 (0.50) | CA2GABRA1GABRB2TSHRALDH1A1 | |
| SCHEMBL2495517 | 0.74 | TSHR (0.45) | CA2GABRA1GABRB2TSHRALDH1A1 | |
| SCHEMBL9465670 | 0.72 | CYP2A6 (0.39) | CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149743-A | Contacting halostyrene monomer with inifer | THE UNIVERSITY OF AKRON (US) | 1992-09-22 | — | — | US | claimed |
| EP-0468041-A4 | HALOGEN TERMINATED POLY(HALOSTYRENES) AND A PROCESS FOR THE PREPARATION THEREOF | — | 1992-07-22 | — | — | EP | claimed |
| EP-0468041-A1 | HALOGEN TERMINATED POLY(HALOSTYRENES) AND A PROCESS FOR THE PREPARATION THEREOF | The University of Akron (US) | 1992-01-29 | — | — | EP | claimed |
| WO-1991012281-A1 | HALOGEN TERMINATED POLY(HALOSTYRENES) AND A PROCESS FOR THE PREPARATION THEREOF | THE UNIVERSITY OF AKRON (US) | 1991-08-22 | — | — | WO | claimed |