SCHEMBL672576

SCHEMBL672576

CC(C)(Cl)c1ccccc1C(C)(C)Cl

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.43
ALDH1A1 P00352 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
CA2 P00918 1/20 0.39
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
MAPK1 P28482 1/20 0.33
KIF11 P52732 1/20 0.32
KCNN4 O15554 1/20 0.32
LMNA P02545 2/20 0.32
ACHE P22303 2/20 0.32
TAAR1 Q96RJ0 2/20 0.31
CYP1A2 P05177 1/20 0.31
ALOX15 P16050 1/20 0.31
SLC6A2 P23975 1/20 0.31
ALOX12 P18054 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29913900 1.00 TSHR (0.43) TSHRALDH1A1TDP1CA2GABRA1
SCHEMBL6683028 0.83 KCNN4 (0.46) TSHRALDH1A1TDP1CA2MAPK1
SCHEMBL2495517 0.83 TSHR (0.45) TSHRALDH1A1TDP1CA2GABRA1
SCHEMBL30343002 0.81 CA2 (0.41) TSHRALDH1A1TDP1CA2MAPK1
SCHEMBL11355317 0.81 ALDH1A1 (0.65) TSHRALDH1A1TDP1CA2GABRA1
SCHEMBL12557615 0.81 ACHE (0.40) TSHRALDH1A1TDP1CA2KIF11
SCHEMBL6683583 0.81 CA2 (0.41) TSHRALDH1A1TDP1CA2MAPK1
SCHEMBL14347039 0.79 CA2 (0.40) TSHRALDH1A1TDP1CA2GABRA1
SCHEMBL536698 0.79 CA2 (0.40) TSHRALDH1A1TDP1CA2GABRA1
SCHEMBL10456271 0.77 P2RX7 (0.36) TSHRALDH1A1TDP1CA2GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6515083-B2 Cationic polymerization of a monomers comprising isobutylene and monomer component whose major monomer is not isobutylene in presence of initiator and in a mixed solvent containing a monohalogenated hydrocarbon and hydrocarbon KANEKA CORPORATION (JP) 2003-02-04 US claimed
EP-0949282-B1 Process for producing isobutylene block copolymer KANEKA CORP (JP) 2002-10-16 EP claimed
US-20020082354-A1 Process for producing isobutylene block copolymer KANEKA CORPORATION (JP) 2002-06-27 US claimed
EP-0949282-A2 Process for producing isobutylene block copolymer KANEKA CORPORATION (JP) 1999-10-13 EP claimed
EP-0468041-A4 HALOGEN TERMINATED POLY(HALOSTYRENES) AND A PROCESS FOR THE PREPARATION THEREOF 1992-07-22 EP claimed
EP-0468041-A1 HALOGEN TERMINATED POLY(HALOSTYRENES) AND A PROCESS FOR THE PREPARATION THEREOF The University of Akron (US) 1992-01-29 EP claimed
WO-1991012281-A1 HALOGEN TERMINATED POLY(HALOSTYRENES) AND A PROCESS FOR THE PREPARATION THEREOF THE UNIVERSITY OF AKRON (US) 1991-08-22 WO claimed
EP-0083685-B1 MANUFACTURE OF DIISOCYANATES AMERICAN CYANAMID COMPANY (US) 1985-03-06 EP claimed
JP-11286525-A None JP disclosed
JP-3174403-A None JP disclosed
EP-4407003-B1 RESIN COMPOSITION AND MOLDED ARTICLE THEREOF TEIJIN LTD (JP) 2026-04-29 EP disclosed
EP-3266829-B1 RESIN COMPOSITION AND RESIN MOLDED ARTICLE ZEON CORP (JP) 2025-03-12 EP disclosed
CN-118599046-A Soluble polyvinyl aromatic copolymer and preparation method and application thereof 青岛玄道科技有限公司 2024-09-06 CN disclosed
EP-4407003-A1 RESIN COMPOSITION AND MOLDED ARTICLE THEREOF Teijin Limited (JP) 2024-07-31 EP disclosed
EP-0130313-A2 Oligomers and homopolymers of meta- or para-isopropenyl-alpha,alpha-dimethylbenzylisocyanate AMERICAN CYANAMID COMPANY (US) 1985-01-09 EP disclosed
US-4399073-A FROM THE HALIDE AND ALKALI METAL CYANATE, WATER AMERICAN CYANAMID COMPANY (US) 1983-08-16 US disclosed
EP-0075771-A1 Phenols, process for their production and their use as stabilizers for polymers BAYER AG (DE) 1983-04-06 EP disclosed
US-4276394-A HALOGENATED POLYMERS OF CATIONICALLY POLYMERIZABLE OFEFINS THE UNIVERSITY OF AKRON (US) 1981-06-30 US disclosed
US-4204075-A PURIFICATION PENNWALT CORPORATION (US) 1980-05-20 US disclosed
US-4133835-A REACTING AN OLEFIN, A HALIDE, AND A HYDROPEROXIDE PENNWALT CORPORATION (US) 1979-01-09 US disclosed