Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42682 | 0.77 | — | — | |
| Sulfuric Acid SCHEMBL9723006 | 0.76 | CYP2D6 (0.30) | CYP2D6 | |
| Hydrochloric Acid SCHEMBL7047737 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL9543054 | 0.73 | — | — | |
| SCHEMBL4204702 | 0.73 | — | — | |
| Ammonia Solution, Strong SCHEMBL4612126 | 0.73 | — | — | |
| Sulfuric Acid SCHEMBL11140702 | 0.72 | — | — | |
| Potassium Ion SCHEMBL29990843 | 0.71 | CYP2D6 (0.35) | CYP2D6GMNNALDH1A1LMNATP53 | |
| Sulfuric Acid SCHEMBL9745986 | 0.70 | ALDH1A1 (0.45) | GMNNALDH1A1LMNATP53TSHR | |
| Propane SCHEMBL18640695 | 0.70 | CYP2D6 (0.83) | CYP2D6KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462980-A4 | PLATINUM PHARMACEUTICAL AGENTS | — | 1992-03-11 | — | — | EP | disclosed |
| EP-0462980-A1 | PLATINUM PHARMACEUTICAL AGENTS | GEORGETOWN UNIVERSITY (US) | 1992-01-02 | — | — | EP | disclosed |
| US-4946954-A | ANTICARCINOGENIC AGENTS | GEORGETOWN UNIVERSITY (US) | 1990-08-07 | — | — | US | disclosed |
| WO-1990008157-A1 | PLATINUM PHARMACEUTICAL AGENTS | GEORGETOWN UNIVERSITY (US) | 1990-07-26 | — | — | WO | disclosed |