Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28858107 | 1.00 | ALDH1A1 (0.45) | ALDH1A1LMNATP53TSHRGMNN | |
| Sulfuric Acid SCHEMBL15710440 | 0.96 | LMNA (0.43) | ALDH1A1LMNATP53TSHRGMNN | |
| Sulfuric Acid SCHEMBL1627398 | 0.92 | ALDH1A1 (0.45) | ALDH1A1LMNATP53TSHRGMNN | |
| Sulfuric Acid SCHEMBL2943169 | 0.92 | ALDH1A1 (0.45) | ALDH1A1LMNATP53TSHRGMNN | |
| Sulfuric Acid SCHEMBL1889469 | 0.92 | ALDH1A1 (0.45) | ALDH1A1LMNATP53TSHRGMNN | |
| Sulfuric Acid SCHEMBL11549839 | 0.92 | ALDH1A1 (0.45) | ALDH1A1LMNATP53TSHRGMNN | |
| Sulfuric Acid SCHEMBL3051587 | 0.92 | ALDH1A1 (0.45) | ALDH1A1LMNATP53TSHRGMNN | |
| Sulfuric Acid SCHEMBL11238338 | 0.92 | ALDH1A1 (0.45) | ALDH1A1LMNATP53TSHRGMNN | |
| Sulfuric Acid SCHEMBL3902475 | 0.92 | ALDH1A1 (0.45) | ALDH1A1LMNATP53TSHRGMNN | |
| Sulfuric Acid SCHEMBL3145097 | 0.92 | ALDH1A1 (0.45) | ALDH1A1LMNATP53TSHRGMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021213455-A1 | DRUG COMBINATION AND USE THEREOF | 浙江养生堂天然药物研究所有限公司 (CN) | 2021-10-28 | — | — | WO | disclosed |
| US-5142075-A | Anti-tumor platinum(II) complexes and process for the preparation thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1992-08-25 | — | — | US | disclosed |