Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10976123 | 0.82 | CNR2 (0.42) | POLBGBA1MMECNR2MAPK1 | |
| SCHEMBL2517311 | 0.82 | TSHR (0.46) | POLBMMECNR2MAPK1MEN1 | |
| SCHEMBL29279682 | 0.81 | HTT (0.41) | POLBMMECNR2MAPK1MEN1 | |
| SCHEMBL10895395 | 0.81 | MEN1 (0.46) | POLBMMECNR2MAPK1MEN1 | |
| SCHEMBL2487911 | 0.81 | CNR2 (0.41) | POLBMMECNR2MAPK1MEN1 | |
| SCHEMBL372364 | 0.81 | ALDH1A1 (0.42) | POLBGBA1MMECNR2GPR88 | |
| SCHEMBL503906 | 0.81 | KMT2A (0.48) | POLBCNR2MAPK1MEN1ALDH1A1 | |
| SCHEMBL11069820 | 0.81 | SOAT1 (0.44) | POLBMMECNR2MAPK1MEN1 | |
| SCHEMBL9620287 | 0.79 | PPARG (0.49) | CNR2ALDH1A1MAPTCYSLTR2CYSLTR1 | |
| SCHEMBL8666771 | 0.79 | PPARG (0.49) | CNR2ALDH1A1MAPTCYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0465577-A1 | CATALYZED REPORTER DEPOSITION. | DU PONT (US) | 1992-01-15 | — | — | EP | disclosed |
| WO-1990011523-A2 | CATALYZED REPORTER DEPOSITION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-10-04 | — | — | WO | disclosed |