SCHEMBL9614745

SCHEMBL9614745

Nc1cc(CC(O)=S)c(Cl)cc1F

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.31
ERCC1 P07992 1/20 0.30
ERCC4 Q92889 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10547394 0.79
SCHEMBL17542809 0.78 GAA (0.31)
SCHEMBL10543892 0.77 L3MBTL1 (0.34) ERCC1ERCC4
SCHEMBL8879998 0.77 GAA (0.33)
SCHEMBL8967810 0.74 HPGD (0.35) PKM
SCHEMBL10714231 0.73 GAA (0.42)
SCHEMBL17542822 0.73 GRIN2D (0.41)
SCHEMBL17434589 0.73 GAA (0.33)
SCHEMBL9614679 0.72 ATM (0.38)
SCHEMBL9419310 0.72 POLB (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4801408-A 3-AMINO-4-FLUORO-6-HALOPHENYLTHIOACETIC ACIDS, 5-SUBSTITUTED ACETANILIDES, HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-01-31 US claimed
JP-60248663-A None JP disclosed
JP-4108770-A None JP disclosed
JP-H04108770-A PRODUCTION OF 5-AMINO-2-CHLORO-4-FLUOROTHIOPHENOL AND INTERMEDIATE THEREFOR IHARA CHEM IND CO LTD 1992-04-09 JP disclosed
US-4801408-A 3-AMINO-4-FLUORO-6-HALOPHENYLTHIOACETIC ACIDS, 5-SUBSTITUTED ACETANILIDES, HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-01-31 US disclosed
EP-0126419-B1 2-SUBSTITUTED PHENYL-4,5,6,7-TETRAHYDRO-2H-ISOINDOLE-1,3-DIONES, AND THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-08-17 EP disclosed
US-4709049-A HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-11-24 US disclosed
US-4684397-A HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-08-04 US disclosed
JP-S60248663-A AMINOPHENYLTHIOACETIC ACID COMPOUND AND ITS PREPARATION SUMITOMO CHEM CO LTD 1985-12-09 JP disclosed
EP-0126419-A1 2-Substituted phenyl-4,5,6,7-tetrahydro-2H-isoindole-1,3-diones, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-11-28 EP disclosed