SCHEMBL8879998

SCHEMBL8879998

Nc1cc(CO)c(Cl)cc1F

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.33
ALDH1A1 P00352 1/20 0.32
TAAR1 Q96RJ0 1/20 0.31
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17542809 0.84 GAA (0.31) GAAALDH1A1
SCHEMBL13375339 0.82 GAA (0.46) GAAALDH1A1CA12CA1CA2
SCHEMBL3824032 0.82 POLB (0.33) GAAALDH1A1TAAR1
SCHEMBL6192193 0.80 GPR84 (0.37) ALDH1A1
SCHEMBL10642362 0.80 GAA (0.50) GAAALDH1A1CA12CA1CA2
SCHEMBL18422043 0.80 ALDH1A1 (0.36) ALDH1A1
SCHEMBL17542822 0.79 GRIN2D (0.41) GAAALDH1A1CA12CA1CA2
SCHEMBL17434589 0.79 GAA (0.33) GAAALDH1A1
SCHEMBL13862141 0.78 RAD52 (0.37) ALDH1A1CA12CA1CA2CA7
SCHEMBL9614745 0.77 PKM (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5631209-A ALGICIDES ROHM AND HAAS COMPANY (US) 1997-05-20 US disclosed
US-5502027-A ALGICIDES ROHM AND HAAS COMPANY (US) 1996-03-26 US disclosed
EP-0415642-B1 Glutarimides ROHM & HAAS (US) 1995-12-06 EP disclosed
US-5393735-A N-(halo-oxy-)phenyl substituted cyclic imides ROHM AND HAAS COMPANY (US) 1995-02-28 US disclosed
EP-0415641-B1 Substituted glutaramic acids and derivatives ROHM & HAAS (US) 1994-01-19 EP disclosed
US-5238908-A HERBICIDAL GLUTARAMIC ACIDS AND DERIVATIVES ROHM AND HAAS COMPANY (US) 1993-08-24 US disclosed
EP-0415641-A1 Substituted glutaramic acids and derivatives ROHM AND HAAS COMPANY (US) 1991-03-06 EP disclosed
EP-0415642-A1 Glutarimides ROHM AND HAAS COMPANY (US) 1991-03-06 EP disclosed
US-4846882-A HALOBENZYL DERIVATIVES FMC CORPORATION (US) 1989-07-11 US disclosed
EP-0289910-A2 Substituted tetrahydrophthalimides, process for their preparation and their use as herbicides HOECHST AKTIENGESELLSCHAFT (DE) 1988-11-09 EP disclosed
WO-1987007602-A2 N-(5-SUBSTITUTED METHYLENE) PHENYL HERBICIDES RHONE-POULENC AGROCHIMIE (FR) 1987-12-17 WO disclosed
CN-87100152-A The compound of weeding 1987-08-12 CN disclosed
WO-1987004049-A1 N-SUBSTITUTED TETRAHYDROPHTHALIMIDE HERBICIDAL COMPOUNDS AND INTERMEDIATES THEREFOR FMC CORPORATION (US) 1987-07-16 WO disclosed