Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 5/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.53 |
| ▸ | PDE5A | O76074 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PDE1A | P54750 | 1/20 | 0.48 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.48 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9707700 | 0.81 | AGTR1 (0.42) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL1945463 | 0.81 | ADORA3 (0.65) | ADORA1ADORA3ADORA2AADORA2BPDE5A | |
| SCHEMBL13789814 | 0.79 | PDE5A (0.85) | PDE5ATSHRHSD17B10 | |
| SCHEMBL13789817 | 0.78 | PDE5A (0.85) | PDE5ATSHRHSD17B10 | |
| SCHEMBL555828 | 0.77 | ADORA1 (0.63) | ADORA1ADORA3ADORA2AADORA2BPDE5A | |
| SCHEMBL9708698 | 0.77 | ADORA3 (0.43) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL3235728 | 0.76 | MAPT (0.49) | ADORA1ADORA3ADORA2AADORA2BLMNA | |
| SCHEMBL9708209 | 0.76 | AGTR1 (0.41) | ADORA1ADORA3 | |
| SCHEMBL13789821 | 0.76 | PDE5A (0.53) | ADORA1ADORA3ADORA2APDE5ALMNA | |
| SCHEMBL13789758 | 0.75 | PDE5A (0.64) | ADORA1ADORA3PDE5ATSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502043-A1 | UTILIZATION OF XANTHINES, OPTIONALLY INCORPORATED IN LIPOSOMES IN ORDER TO HELP THE PIGMENTATION OF SKIN OR HAIR. | LVMH RECH (FR) | 1992-09-09 | — | — | EP | claimed |
| WO-1991007945-A1 | UTILIZATION OF XANTHINES, OPTIONALLY INCORPORATED IN LIPOSOMES IN ORDER TO HELP THE PIGMENTATION OF SKIN OR HAIR | LVMH RECHERCHE (FR) | 1991-06-13 | — | — | WO | claimed |