Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 4/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15510700 | 0.87 | KDM4E (0.40) | SMN1; SMN2LMNAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL948199 | 0.80 | KDM4E (0.50) | SMN1; SMN2LMNAALDH1A1KDM4EPRKAB2 | |
| SCHEMBL15758954 | 0.79 | ALPL (0.45) | SMN1; SMN2LMNAALDH1A1KDM4EHPGD | |
| SCHEMBL1776218 | 0.79 | CA12 (0.45) | CA12PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL15758825 | 0.79 | CA12 (0.45) | TSHRCA12PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL9353501 | 0.76 | PRKAG1 (0.53) | SMN1; SMN2ALDH1A1KDM4EHPGDCYP2D6 | |
| SCHEMBL16109091 | 0.76 | KDM4E (0.36) | SMN1; SMN2LMNAALDH1A1KDM4ECA9 | |
| SCHEMBL16209016 | 0.75 | KDM4E (0.36) | TSHRSMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL30140003 | 0.74 | POLB (0.51) | ALDH1A1HSD17B10POLBCYP2D6TDP1 | |
| SCHEMBL3383809 | 0.72 | KDM4E (0.46) | SMN1; SMN2LMNAALDH1A1KDM4EPRKAB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511246-A1 | WATER-SOLUBLE DYES WHICH REACT WITH FIBRES, PROCESS FOR PRODUCING THEM AND THEIR USE. | HOECHST AG (DE) | 1992-11-04 | — | — | EP | disclosed |