Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTR5A | P47898 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9696491 | 0.98 | KDM4E (0.56) | HTR2AHTR2CHDAC1HDAC6KDM4E | |
| SCHEMBL2357949 | 0.88 | HDAC1 (0.55) | HTR2AHTR2CHDAC1HDAC6KDM4E | |
| SCHEMBL30873508 | 0.88 | HDAC1 (0.55) | HTR2AHTR2CHDAC1HDAC6KDM4E | |
| SCHEMBL9615110 | 0.85 | NPC1 (0.54) | HTR2AHTR2CHDAC1HDAC6KDM4E | |
| SCHEMBL6422112 | 0.84 | HTR2C (0.55) | HTR2AHTR2CHDAC1HDAC6KDM4E | |
| Hydrochloric Acid SCHEMBL9615105 | 0.84 | KDM4E (0.53) | HTR2AHTR2CHDAC1HDAC6KDM4E | |
| SCHEMBL6422248 | 0.82 | HDAC1 (0.69) | HTR2AHTR2CHDAC1HDAC6KDM4E | |
| SCHEMBL4300297 | 0.82 | HDAC1 (0.53) | HTR2AHTR2CHDAC1HDAC6KDM4E | |
| SCHEMBL12369406 | 0.82 | HDAC1 (0.53) | HTR2AHTR2CHDAC1HDAC6KDM4E | |
| SCHEMBL6422780 | 0.81 | HDAC1 (0.52) | HTR2AHTR2CHDAC1HDAC6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946031-A | Substituted aromatic phenol derivatives of KNa1.1 channel inhibitors | 北京大学 | 2024-04-30 | — | — | CN | disclosed |
| US-5169852-A | Anorexigenic agents | NEUREX CORPORATION (US) | 1992-12-08 | — | — | US | disclosed |
| EP-0520987-A4 | METHOD OF SUPPRESSING APPETITE BY ADMINISTRATION OF TETRAHYDRO--g(b)-CARBOLINE DERIVATIVES. | NEUREX CORP (US) | 1992-05-13 | — | — | EP | disclosed |