Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.54 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.54 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.54 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.53 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9615105 | 0.99 | KDM4E (0.53) | NPC1RAB9AKDM4EPABPC1APOBEC3A | |
| SCHEMBL176660 | 0.88 | SIRT2 (0.66) | NPC1RAB9AKDM4EPABPC1APOBEC3A | |
| SCHEMBL11755016 | 0.88 | NPC1 (0.54) | NPC1RAB9AKDM4EPABPC1APOBEC3A | |
| SCHEMBL9615137 | 0.85 | HTR2A (0.55) | RAB9AKDM4EALDH1A1HTR2AHTR2C | |
| SCHEMBL9615142 | 0.84 | SIRT2 (0.64) | NPC1RAB9AKDM4EPABPC1APOBEC3A | |
| Hydrochloric Acid SCHEMBL9696491 | 0.83 | KDM4E (0.56) | RAB9AKDM4EALDH1A1HTR2AHTR2C | |
| SCHEMBL46293 | 0.83 | HDAC1 (0.52) | KDM4EHTR2AHTR2CALOX15MAPK1 | |
| SCHEMBL9696716 | 0.83 | SIRT2 (0.55) | SIRT2SIRT1HTR6HRH1 | |
| Hydrochloric Acid SCHEMBL9615130 | 0.83 | SIRT2 (0.62) | NPC1RAB9AKDM4EPABPC1APOBEC3A | |
| SCHEMBL4300297 | 0.82 | HDAC1 (0.53) | KDM4EALDH1A1HTR2AHTR2CALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169852-A | Anorexigenic agents | NEUREX CORPORATION (US) | 1992-12-08 | — | — | US | disclosed |
| EP-0520987-A4 | METHOD OF SUPPRESSING APPETITE BY ADMINISTRATION OF TETRAHYDRO--g(b)-CARBOLINE DERIVATIVES. | NEUREX CORP (US) | 1992-05-13 | — | — | EP | disclosed |
| US-4978669-A | ALTERING MACRONUTRIENT PREFERENCE | NEUREX CORPORATION (US) | 1990-12-18 | — | — | US | disclosed |