Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | TACR2 | P21452 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TST | Q16762 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925479 | 0.88 | SCN9A (0.34) | KDM4EALDH1A1LMNATP53HSD17B10 | |
| SCHEMBL9736230 | 0.86 | ESR1 (0.38) | GPR3ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL9735859 | 0.86 | ESR1 (0.38) | GPR3ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL9737334 | 0.86 | ESR1 (0.38) | GPR3ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL5850674 | 0.85 | MPI (0.37) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL31318113 | 0.83 | OPRM1 (0.42) | TP53CYP3A4SCN9A | |
| SCHEMBL13224440 | 0.83 | KMT2A (0.49) | ALDH1A1LMNATP53PTGS1PTGS2 | |
| SCHEMBL15066621 | 0.83 | KMT2A (0.49) | ALDH1A1LMNATP53PTGS1PTGS2 | |
| SCHEMBL8925623 | 0.82 | SCN9A (0.35) | TP53PTGS1PTGS2SCN9A | |
| SCHEMBL19746778 | 0.81 | SCN9A (0.43) | KDM4EALDH1A1HIF1AACHESCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4117385-A | — | — | None | — | — | JP | disclosed |
| JP-H04117385-A | PHOTOCHROMIC COMPOUND | CITIZEN WATCH CO LTD | 1992-04-17 | — | — | JP | disclosed |