SCHEMBL19746778

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10643897	1.00	SCN9A (0.43)	SCN9AHDAC2CBX7CDYL2CDYL
	SCHEMBL30996196	0.95	HDAC2 (0.43)	SCN9AHDAC2CBX7CDYL2CDYL
	SCHEMBL4615673	0.84	ALDH1A1 (0.45)	HDAC2DYRK1AKDM4EALDH1A1GLA
	SCHEMBL13224440	0.82	KMT2A (0.49)	SCN9AALDH1A1MEN1KMT2A
	SCHEMBL31318113	0.82	OPRM1 (0.42)	SCN9AMEN1KMT2A
	SCHEMBL15066621	0.82	KMT2A (0.49)	SCN9AALDH1A1MEN1KMT2A
	SCHEMBL9615201	0.81	GPR3 (0.37)	SCN9AKDM4EALDH1A1HIF1AACHE
	SCHEMBL8925479	0.80	SCN9A (0.34)	SCN9AKDM4EALDH1A1CNR2MEN1
	SCHEMBL19746373	0.78	KMT2A (0.50)	SCN9AALDH1A1GLACNR2MEN1
	SCHEMBL9868831	0.78	KMT2A (0.50)	SCN9AALDH1A1GLACNR2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.