Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | STAT1 | P42224 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | TYR | P14679 | 1/20 | 0.61 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | APP | P05067 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9615338 | 1.00 | NFE2L2 (0.70) | NFE2L2KDM4EALDH1A1POLBPKM | |
| SCHEMBL9615339 | 1.00 | NFE2L2 (0.70) | NFE2L2KDM4EALDH1A1POLBPKM | |
| O-Xylene SCHEMBL27939363 | 0.92 | KDM4E (0.64) | NFE2L2KDM4EALDH1A1POLBPKM | |
| Anisole SCHEMBL27939364 | 0.91 | ALDH1A1 (0.66) | NFE2L2KDM4EALDH1A1POLBPKM | |
| Toluene SCHEMBL27951768 | 0.91 | KDM4E (0.66) | NFE2L2KDM4EALDH1A1POLBPKM | |
| Ethylbenzene SCHEMBL27951882 | 0.90 | ALDH1A1 (0.70) | NFE2L2KDM4EALDH1A1POLBPKM | |
| SCHEMBL1259775 | 0.89 | TYR (0.78) | NFE2L2KDM4EALDH1A1POLBPKM | |
| Isopropylbenzene SCHEMBL27939367 | 0.88 | ALDH1A1 (0.62) | NFE2L2KDM4EALDH1A1POLBPKM | |
| Phenetole SCHEMBL27939415 | 0.88 | MAPT (0.64) | NFE2L2KDM4EALDH1A1POLBPKM | |
| SCHEMBL13002039 | 0.86 | HPGD (0.80) | NFE2L2KDM4EALDH1A1POLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4134028-A | — | — | None | — | — | JP | disclosed |
| JP-H04134028-A | CEREBRAL FUNCTION-IMPROVING DRUG AND ANTIDEPRESSANT | KANEGAFUCHI CHEM IND CO LTD | 1992-05-07 | — | — | JP | disclosed |