SCHEMBL9615360

SCHEMBL9615360

CCCCC(C)(CC)c1cc(C(C)(C)c2ccccc2)cc(C(=O)O)c1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR5A2 O00482 1/20 0.44
NR5A1 Q13285 1/20 0.44
CA12 O43570 3/20 0.36
CA9 Q16790 3/20 0.36
ALDH1A1 P00352 2/20 0.35
ESR1 P03372 1/20 0.35
CYP3A4 P08684 1/20 0.35
ESR2 Q92731 1/20 0.35
KIF11 P52732 1/20 0.34
AKR1C2 P52895 1/20 0.34
AKR1C1 Q04828 1/20 0.34
BCL2 P10415 1/20 0.34
MCL1 Q07820 1/20 0.34
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
KDM4E B2RXH2 2/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9652108 0.82 NR5A2 (0.41) NR5A2NR5A1ALDH1A1ESR1CYP3A4
SCHEMBL1129729 0.80 ESR1 (0.46) NR5A2NR5A1ALDH1A1ESR1CYP3A4
SCHEMBL5143833 0.80 NR5A2 (0.43) NR5A2NR5A1CNR1CNR2
SCHEMBL7084776 0.79 ESR1 (0.44) NR5A2NR5A1ALDH1A1ESR1CYP3A4
SCHEMBL9615386 0.79 NR5A2 (0.48) NR5A2NR5A1ALDH1A1ESR1CYP3A4
Water SCHEMBL9852464 0.79 ESR1 (0.44) NR5A2NR5A1ALDH1A1ESR1CYP3A4
Water SCHEMBL9852463 0.78 ESR1 (0.43) NR5A2NR5A1ALDH1A1ESR1CYP3A4
SCHEMBL9251401 0.77 CYP2C9 (0.39) NR5A2NR5A1ALDH1A1ESR1CYP3A4
SCHEMBL9652251 0.75 PTPN1 (0.45) ALDH1A1ESR1CYP3A4ESR2AKR1C2
SCHEMBL9615388 0.74 NR5A2 (0.45) NR5A2NR5A1ALDH1A1ESR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5128309-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1992-07-07 US disclosed