SCHEMBL9652108

SCHEMBL9652108

CCC(C)(C)c1cc(C(C)(C)c2ccccc2)cc(C(=O)O)c1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR5A2 O00482 1/20 0.41
NR5A1 Q13285 1/20 0.41
CYP3A4 P08684 2/20 0.40
ALDH1A1 P00352 2/20 0.40
ESR1 P03372 2/20 0.40
ESR2 Q92731 2/20 0.40
CNR1 P21554 2/20 0.38
CNR2 P34972 2/20 0.38
HMGB1 P09429 1/20 0.37
CXCL12 P48061 1/20 0.37
CYP2C9 P11712 3/20 0.36
TSHR P16473 2/20 0.36
THRB P10828 1/20 0.36
HPGD P15428 1/20 0.36
ALOX12 P18054 1/20 0.36
ATIC P31939 1/20 0.36
HSD17B10 Q99714 1/20 0.36
PTPN1 P18031 4/20 0.36
PTPN2 P17706 3/20 0.36
PTPN6 P29350 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9251401 0.89 CYP2C9 (0.39) NR5A2NR5A1CYP3A4ALDH1A1ESR1
SCHEMBL1129729 0.87 ESR1 (0.46) NR5A2NR5A1CYP3A4ALDH1A1ESR1
SCHEMBL9615386 0.85 NR5A2 (0.48) NR5A2NR5A1CYP3A4ALDH1A1ESR1
Water SCHEMBL9852464 0.85 ESR1 (0.44) NR5A2NR5A1CYP3A4ALDH1A1ESR1
SCHEMBL7084776 0.85 ESR1 (0.44) NR5A2NR5A1CYP3A4ALDH1A1ESR1
SCHEMBL7782928 0.85 RXRA (0.43) NR5A2NR5A1ALDH1A1HMGB1CXCL12
Water SCHEMBL9852463 0.84 ESR1 (0.43) NR5A2NR5A1CYP3A4ALDH1A1ESR1
SCHEMBL9166132 0.84 RXRA (0.42) NR5A2NR5A1ALDH1A1HMGB1CXCL12
SCHEMBL9615360 0.82 NR5A2 (0.44) NR5A2NR5A1CYP3A4ALDH1A1ESR1
SCHEMBL9652251 0.81 PTPN1 (0.45) CYP3A4ALDH1A1ESR1ESR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5141557-A Mixture of benzoic acid salt, anionic surfactant, and novolak phenolic resin BROTHER KOGYO KABUSHIKI KAISHA (JP) 1992-08-25 US disclosed