Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | PRKCG | P05129 | 3/20 | 0.34 |
| ▸ | PRKCB | P05771 | 3/20 | 0.34 |
| ▸ | PRKCA | P17252 | 3/20 | 0.34 |
| ▸ | PRKCH | P24723 | 3/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9615551 | 0.94 | TSHR (0.37) | TSHRPTGS2POLBAPEX1HTT | |
| SCHEMBL9615547 | 0.92 | POLB (0.38) | TSHRPTGS2POLBAPEX1HTT | |
| SCHEMBL9615565 | 0.88 | ALDH1A1 (0.45) | TSHRPTGS2POLBAPEX1HTT | |
| SCHEMBL12789621 | 0.84 | TSHR (0.42) | TSHRPTGS2POLBAPEX1HTT | |
| SCHEMBL4097168 | 0.82 | TSHR (0.45) | TSHRPTGS2POLBAPEX1HTT | |
| SCHEMBL14730856 | 0.82 | TSHR (0.45) | TSHRPTGS2POLBAPEX1HTT | |
| SCHEMBL9615555 | 0.82 | ALDH1A1 (0.45) | TSHRPTGS2TDP1ALDH1A1KDM4E | |
| SCHEMBL9615545 | 0.81 | POLB (0.41) | TSHRPTGS2POLBAPEX1HTT | |
| SCHEMBL4882782 | 0.81 | TSHR (0.44) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL10585165 | 0.81 | ALDH1A1 (0.39) | TSHRPTGS2POLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5096799-A | Carboxy grou-containing binder, photoinitiator with lophine dimer, carboxy and ester group-containing compound to prevent discoloration, monomer; storage stable | FUJI PHOTO FILM CO., LTD. (JP) | 1992-03-17 | — | — | US | disclosed |