SCHEMBL9615565

SCHEMBL9615565

C=C(C)C(=O)OCC(COC(=O)C(=C)C)OC(=O)c1ccccc1C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.45
TSHR P16473 5/20 0.43
PTGS2 P35354 2/20 0.41
ALOX15 P16050 1/20 0.39
CYP3A4 P08684 2/20 0.39
CA2 P00918 1/20 0.39
TDP1 Q9NUW8 2/20 0.37
POLB P06746 1/20 0.37
APEX1 P27695 1/20 0.37
HTT P42858 1/20 0.37
PRSS1 P07477 1/20 0.37
PRSS2 P07478 1/20 0.37
PRSS3 P35030 1/20 0.37
HSD17B10 Q99714 3/20 0.37
TP53 P04637 1/20 0.37
KDM4E B2RXH2 2/20 0.36
ESR1 P03372 1/20 0.36
ITGB3 P05106 1/20 0.36
ITGA2B P08514 1/20 0.36
HMGB1 P09429 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12789621 0.95 TSHR (0.42) ALDH1A1TSHRPTGS2ALOX15CYP3A4
SCHEMBL9615555 0.93 ALDH1A1 (0.45) ALDH1A1TSHRPTGS2ALOX15CYP3A4
SCHEMBL9615545 0.93 POLB (0.41) ALDH1A1TSHRPTGS2CYP3A4TDP1
SCHEMBL12791621 0.92 ALDH1A1 (0.39) ALDH1A1TSHRPTGS2ALOX15CYP3A4
SCHEMBL8923052 0.91 ALDH1A1 (0.46) ALDH1A1TSHRPTGS2ALOX15CYP3A4
SCHEMBL10339546 0.91 ALDH1A1 (0.43) ALDH1A1TSHRPTGS2ALOX15CYP3A4
SCHEMBL3268987 0.90 ALDH1A1 (0.43) ALDH1A1TSHRPTGS2ALOX15CYP3A4
SCHEMBL9615564 0.88 TSHR (0.40) ALDH1A1TSHRPTGS2CYP3A4CA2
SCHEMBL2779922 0.88 ALDH1A1 (0.53) ALDH1A1TSHRALOX15CYP3A4TDP1
SCHEMBL14730856 0.86 TSHR (0.45) ALDH1A1TSHRPTGS2TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5096799-A Carboxy grou-containing binder, photoinitiator with lophine dimer, carboxy and ester group-containing compound to prevent discoloration, monomer; storage stable FUJI PHOTO FILM CO., LTD. (JP) 1992-03-17 US disclosed
US-4551215-A EPOXY COMPOUND, PHOTOPOLYMERIZABLE COMPOUND HAVING CARBOXYL, AND PHOTOSENSITIZER TOYO BOSEKI KABUSHIKI KAISHA (JP) 1985-11-05 US disclosed