Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PAK4 | O96013 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | ROS1 | P08922 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9615758 | 0.82 | NOTUM (0.39) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL9615669 | 0.75 | KMT2A (0.37) | CYP1A2CYP2C19CYP2D6MAPTKMT2A | |
| SCHEMBL9945358 | 0.74 | CYP19A1 (0.41) | MEN1KMT2A | |
| SCHEMBL10361156 | 0.66 | NOTUM (0.39) | NPC1RAB9ASMN1; SMN2ALDH1A1ALOX15 | |
| SCHEMBL11583500 | 0.66 | CDC7 (0.55) | CYP1A2CDC7PLK4AURKAPDPK1 | |
| SCHEMBL18456788 | 0.64 | CNR2 (0.43) | CYP1A2CYP3A4CYP2C9CYP2C19CDC7 | |
| SCHEMBL11017596 | 0.64 | CYP19A1 (0.40) | ALDH1A1ALOX15MEN1KMT2AMAPK1 | |
| SCHEMBL10841169 | 0.63 | KMT2A (0.42) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL28883 | 0.63 | L3MBTL1 (0.79) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL10989896 | 0.63 | MAPT (0.61) | CLK4MAPTPDK1PDK2PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4154770-A | — | — | None | — | — | JP | disclosed |
| JP-H04154770-A | TRIAZOLECARBOXLIC ACID AMIDE DERIVATIVE AND AGRICULTURAL AND HORTICULTURAL GERMICIDE | HOKKO CHEM IND CO LTD | 1992-05-27 | — | — | JP | disclosed |