Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.79 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.66 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.66 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.66 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383652 | 0.94 | L3MBTL1 (0.70) | L3MBTL1PDK1PDK2PDK3PDK4 | |
| SCHEMBL7733701 | 0.89 | L3MBTL1 (1.00) | L3MBTL1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11537675 | 0.86 | PDK1 (0.59) | L3MBTL1PDK1PDK2PDK3PDK4 | |
| SCHEMBL19853109 | 0.84 | PDK1 (0.62) | L3MBTL1PDK1PDK2PDK3PDK4 | |
| Hydrochloric Acid SCHEMBL19841199 | 0.82 | PDK1 (0.60) | L3MBTL1PDK1PDK2PDK3PDK4 | |
| SCHEMBL11249289 | 0.82 | PDK1 (0.60) | L3MBTL1PDK1PDK2PDK3PDK4 | |
| SCHEMBL7424794 | 0.82 | PDK1 (0.60) | L3MBTL1PDK1PDK2PDK3PDK4 | |
| SCHEMBL13171374 | 0.82 | RHOC (0.64) | L3MBTL1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL10386145 | 0.81 | PDK1 (0.58) | L3MBTL1PDK1PDK2PDK3PDK4 | |
| SCHEMBL1422823 | 0.81 | L3MBTL1 (0.83) | L3MBTL1MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 360 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954705-A | Indole derivative and preparation method thereof | 南阳师范学院 | 2025-05-09 | — | — | CN | claimed |
| CN-116808967-A | 4-chloro-2-trifluoroacetyl aniline hydrochloride micro-channel reactor and synthesis method | 江西华洲科技有限公司 | 2023-09-29 | — | — | CN | claimed |
| CN-108947855-B | Synthesis method of efavirenz key intermediate | 江苏沙星化工有限公司 | 2021-10-22 | — | — | CN | claimed |
| CN-108947855-A | A kind of synthetic method of efavirenz key intermediate | 江苏沙星化工有限公司 | 2018-12-07 | — | — | CN | claimed |
| US-20250197360-A1 | NOVEL DIAZEPINES THAT TARGET YELLOW FEVER VIRUS NON-STRUCTURAL 4B (NS4B) PROTEIN AND THEIR METHOD OF USE | BARUCH S. BLUMBERG INSTITUTE | 2025-06-19 | — | — | US | disclosed |
| CN-119954705-A | Indole derivative and preparation method thereof | 南阳师范学院 | 2025-05-09 | — | — | CN | disclosed |
| CN-222641616-U | Processing apparatus of lithium chloride crystallization is precipitated in waste liquid | 黄石市博尔化工有限公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-119072467-A | Novel diazapine compounds targeting yellow fever virus non-structural 4B (NS 4B) protein and methods of use thereof | 巴鲁克斯布伦博格研究所 | 2024-12-03 | — | — | CN | disclosed |
| CN-220182843-U | Waste liquid treatment device | 江西华洲科技有限公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-116808967-A | 4-chloro-2-trifluoroacetyl aniline hydrochloride micro-channel reactor and synthesis method | 江西华洲科技有限公司 | 2023-09-29 | — | — | CN | disclosed |
| WO-2023172726-A1 | NOVEL DIAZEPINES THAT TARGET YELLOW FEVER VIRUS NON-STRUCTURAL 4B (NS4B) PROTEIN AND THEIR METHOD OF USE | BARUCH S. BLUMBERG INSTITUTE (US) | 2023-09-14 | — | — | WO | disclosed |
| WO-2023172726-A1 | NOVEL DIAZEPINES THAT TARGET YELLOW FEVER VIRUS NON-STRUCTURAL 4B (NS4B) PROTEIN AND THEIR METHOD OF USE | BARUCH S. BLUMBERG INSTITUTE (US) | 2023-09-14 | — | — | WO | disclosed |
| EP-0663899-A4 | SUBSTITUTED KYNURENINES, A PROCESS FOR THEIR PREPARATION, AND USE AS MEDICAMENTS. | UNIV MARYLAND (US) | 1996-01-17 | — | — | EP | disclosed |
| WO-1995020389-A1 | BENZOXAZINONES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE | MERCK & CO., INC. (US) | 1995-08-03 | — | — | WO | disclosed |
| EP-0663899-A1 | SUBSTITUTED KYNURENINES, A PROCESS FOR THEIR PREPARATION, AND USE AS MEDICAMENTS | THE UNIVERSITY OF MARYLAND AT BALTIMORE (US) | 1995-07-26 | — | — | EP | disclosed |
| WO-1995004714-A1 | SUBSTITUTED KYNURENINES, A PROCESS FOR THEIR PREPARATION, AND USE AS MEDICAMENTS | UNIVERSITY OF MARYLAND AT BALTIMORE (US) | 1995-02-16 | — | — | WO | disclosed |
| WO-1994003440-A1 | BENZOXAZINONES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE | MERCK & CO., INC. (US) | 1994-02-17 | — | — | WO | disclosed |
| EP-0582455-A1 | Benzoxazinones as inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1994-02-09 | — | — | EP | disclosed |
| EP-0070171-B1 | NOVEL PIPERIDINE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | KYOWA HAKKO KOGYO CO., LTD (JP) | 1986-10-15 | — | — | EP | disclosed |
| EP-0070171-A1 | Novel piperidine derivatives, processes for preparation thereof and pharmaceutical compositions containing same | KYOWA HAKKO KOGYO CO., LTD (JP) | 1983-01-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250197360-A1 | NOVEL DIAZEPINES THAT TARGET YELLOW FEVER VIRUS NON-STRUCTURAL 4B (NS4B) PROTEIN AND THEIR METHOD OF USE | CUL4B, BRD4, CUL4A | L3MBTL1 3709/4885PDK1 3874/4885PDK2 1600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.