SCHEMBL9615907

SCHEMBL9615907

CCN(CC)c1ccc(C#Cc2c3ccccc3c(C#Cc3ccc(N(CC)CC)cc3)c3ccccc23)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
ALDH3A1 P30838 1/20 0.44
ALDH1A3 P47895 1/20 0.44
ACHE P22303 2/20 0.44
MEN1 O00255 5/20 0.44
KMT2A Q03164 5/20 0.44
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
NOX1 Q9Y5S8 2/20 0.44
CNR2 P34972 1/20 0.43
L3MBTL1 Q9Y468 4/20 0.42
MAPK1 P28482 3/20 0.42
TSHR P16473 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
PSMD14 O00487 1/20 0.42
CYP3A4 P08684 1/20 0.42
RECQL P46063 1/20 0.42
GFER P55789 1/20 0.42
KDM1A O60341 1/20 0.42
GAA P10253 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17370955 0.79 CHAT (0.54) ALDH1A1ACHEMEN1KMT2ANPC1
SCHEMBL20223149 0.76 PTPN11 (0.38) NPC1RAB9ACNR2HTTSMN1; SMN2
SCHEMBL20212679 0.76 PTPN11 (0.38) NPC1RAB9ACNR2L3MBTL1HTT
SCHEMBL1108171 0.75 ALDH1A1 (0.56) ALDH1A1ALDH3A1ALDH1A3MEN1KMT2A
SCHEMBL14163996 0.75 L3MBTL1 (0.52) L3MBTL1TDP1ATM
SCHEMBL15947631 0.75 KDM1A (0.40) ALDH1A1ACHEMEN1KMT2ANPC1
SCHEMBL15947626 0.75 KDM1A (0.40) ALDH1A1ACHEMEN1KMT2ANPC1
SCHEMBL15947635 0.75 HTR2C (0.50) ALDH1A1ACHEMEN1KMT2ANPC1
SCHEMBL20223155 0.74 PTPN11 (0.36) NPC1RAB9ACNR2HTTSMN1; SMN2
SCHEMBL13614128 0.73 ALDH1A1 (0.44) ALDH1A1ALDH3A1ALDH1A3ACHEMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4164038-A None JP disclosed
JP-H04164038-A ANTHRACENE DERIVATIVE YAMAMOTO CHEM INC 1992-06-09 JP disclosed