SCHEMBL9616044

SCHEMBL9616044

O=C(CI)OC1CCCCC1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.53
NAAA Q02083 2/20 0.52
HTT P42858 2/20 0.50
CYP19A1 P11511 2/20 0.47
EPHX1 P07099 2/20 0.47
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 3/20 0.37
HPGD P15428 2/20 0.37
HSD17B10 Q99714 1/20 0.37
LMNA P02545 2/20 0.36
RAB9A P51151 1/20 0.36
MIF P14174 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MMP1 P03956 1/20 0.35
MMP9 P14780 1/20 0.35
MMP12 P39900 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4672313 0.84 CYP2C19 (0.55) CYP2C19NAAAHTTCYP19A1EPHX1
SCHEMBL5439382 0.84 CYP2C19 (0.55) CYP2C19NAAAHTTCYP19A1EPHX1
SCHEMBL17860865 0.83 NAAA (0.58) CYP2C19NAAAHTTCYP19A1EPHX1
SCHEMBL17920350 0.81 CYP2C19 (0.57) CYP2C19NAAAHTTCYP19A1EPHX1
SCHEMBL242936 0.81 CYP2C19 (0.57) CYP2C19NAAAHTTCYP19A1EPHX1
SCHEMBL7568980 0.81 NAAA (0.66) CYP2C19NAAAHTTCYP19A1EPHX1
SCHEMBL31069913 0.81 NAAA (0.66) CYP2C19NAAAHTTCYP19A1EPHX1
SCHEMBL258780 0.81 NAAA (0.66) CYP2C19NAAAHTTCYP19A1EPHX1
SCHEMBL4677005 0.81 NAAA (0.52) CYP2C19NAAAHTTCYP19A1EPHX1
SCHEMBL6974663 0.80 NAAA (0.59) CYP2C19NAAAHTTCYP19A1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4182453-A None JP disclosed
WO-2020054874-A1 PHOTOPOLYMERIZATION SENSITIZER 川崎化成工業株式会社 2020-03-19 WO disclosed
JP-H04182453-A OPTICALLY ACTIVE CYCLOHEXYL CARBOXYLATE DERIVATIVE AND ITS PRODUCTION SANKYO CO LTD 1992-06-30 JP disclosed