Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.45 |
| ▸ | ESR1 | P03372 | 8/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | USP7 | Q93009 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1513792 | 0.87 | AHR (0.50) | MMP2MMP3ESR2ESR1HSD17B10 | |
| SCHEMBL2767670 | 0.86 | ESR2 (0.48) | ESR2ESR1HSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL1513663 | 0.80 | MEN1 (0.58) | ESR2ESR1HSD17B10TSHRMEN1 | |
| SCHEMBL2280325 | 0.80 | HSD17B10 (0.48) | ESR2ESR1HSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL28330002 | 0.78 | HSD17B10 (0.46) | ESR2ESR1HSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL28216729 | 0.77 | ESR2 (0.55) | ESR2ESR1HSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL6058676 | 0.77 | MMP2 (0.42) | MMP2MMP3ESR2ESR1USP7 | |
| SCHEMBL9623395 | 0.76 | ABL1 (0.50) | ESR2ESR1HSD17B10CYP3A4MEN1 | |
| SCHEMBL5795293 | 0.76 | ALDH1A1 (0.54) | ESR2ESR1HSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL9441987 | 0.76 | PIM1 (0.52) | ESR2ESR1HSD17B10ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4193842-A | — | — | None | — | — | JP | disclosed |
| JP-H04193842-A | OPTICALLY ACTIVE BIPHENYL DERIVATIVE AND OPTICAL RESOLUTION PROCESS | DAICEL CHEM IND LTD | 1992-07-13 | — | — | JP | disclosed |