Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1664233 | 0.85 | TP53 (0.48) | FOLH1ALDH1A1MAPK1TP53DHODH | |
| SCHEMBL26599226 | 0.82 | NPC1 (0.50) | ALDH1A1TP53CYP3A4SMN1; SMN2KDM4E | |
| SCHEMBL31207954 | 0.82 | NPC1 (0.50) | ALDH1A1TP53CYP3A4SMN1; SMN2KDM4E | |
| SCHEMBL14398355 | 0.81 | KDM4E (0.47) | ALDH1A1CYP3A4ALOX12CYP2C9L3MBTL1 | |
| SCHEMBL1443004 | 0.81 | TP53 (0.61) | NR1H4ALDH1A1MAPK1TP53DHODH | |
| SCHEMBL14398358 | 0.79 | SMN1; SMN2 (0.50) | ALDH1A1CYP3A4ALOX12CYP2C9L3MBTL1 | |
| SCHEMBL29921207 | 0.78 | ALDH1A1 (0.57) | ALDH1A1MAPK1TP53DHODHCYP3A4 | |
| SCHEMBL7370339 | 0.78 | ALDH1A1 (0.57) | ALDH1A1MAPK1TP53DHODHCYP3A4 | |
| SCHEMBL10431721 | 0.76 | FOLH1 (0.49) | NR1H4FOLH1ALDH1A1MAPK1TP53 | |
| SCHEMBL36145 | 0.75 | ALDH1A1 (0.72) | FOLH1ALDH1A1CYP3A4ALOX12CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4193875-A | — | — | None | — | — | JP | disclosed |
| JP-H04193875-A | NEW BIPHENYL DERIVATIVE AND HEPATOPATHY IMPROVER CONTAINING THE SAME | TSUMURA & CO | 1992-07-13 | — | — | JP | disclosed |