Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.33 |
| ▸ | PTPRE | P23469 | 1/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10754874 | 0.72 | KDM4E (0.42) | KMT2AALDH1A1NOTUMNAPRTKDM4E | |
| SCHEMBL20929054 | 0.71 | — | — | |
| SCHEMBL10468545 | 0.66 | GPR84 (0.45) | KMT2AALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL10600088 | 0.65 | KMO (0.43) | KMT2AKDM4EMAPTGAA | |
| SCHEMBL1232001 | 0.64 | CA12 (0.48) | ALDH1A1NOTUMNAPRTPTPRCPTPN2 | |
| SCHEMBL9742694 | 0.64 | KMT2A (0.41) | KMT2AALDH1A1CCR8NAPRTDUSP3 | |
| SCHEMBL26619127 | 0.64 | NAPRT (0.55) | KMT2AALDH1A1NAPRTKDM4EHPGD | |
| SCHEMBL20101949 | 0.62 | KMT2A (0.39) | KMT2AALDH1A1NOTUMCCR8NAPRT | |
| Hydrochloric Acid SCHEMBL17597734 | 0.62 | CA12 (0.46) | ALDH1A1NAPRTPTPRCPTPN2PTPN1 | |
| SCHEMBL3653849 | 0.62 | DPP4 (0.47) | KMT2AALDH1A1CCR8NAPRTPTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4198185-A | — | — | None | — | — | JP | disclosed |
| JP-H04198185-A | ISOTHIAZOLO(5,4-B)PYRIDINE DERIVATIVE | DAINIPPON PHARMACEUT CO LTD | 1992-07-17 | — | — | JP | disclosed |