Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29199108 | 0.86 | TSHR (0.61) | TSHRTDP1ALDH1A1MAPTKMT2A | |
| SCHEMBL10894837 | 0.80 | ALDH1A1 (0.43) | TSHRTDP1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL7902152 | 0.80 | TSHR (0.56) | TSHRTDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL7138835 | 0.80 | TSHR (0.56) | TSHRTDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL7138831 | 0.80 | TSHR (0.56) | TSHRTDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL9092954 | 0.79 | TSHR (0.72) | TSHRTDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL14967822 | 0.77 | TSHR (0.54) | TSHRTDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL14967506 | 0.76 | TSHR (0.52) | TSHRTDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL9690184 | 0.75 | FABP3 (0.46) | TSHRTDP1ALDH1A1SMN1; SMN2ALOX15 | |
| SCHEMBL14967725 | 0.75 | TSHR (0.70) | TSHRTDP1L3MBTL1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440723-A4 | PROCESS FOR PREPARING OPTICALLY ACTIVE GLYCIDATE ESTERS | — | 1992-05-20 | — | — | EP | disclosed |
| EP-0440723-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE GLYCIDATE ESTERS. | SEPRACOR INC (US) | 1991-08-14 | — | — | EP | disclosed |
| WO-1990004643-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE GLYCIDATE ESTERS | SEPRACOR, INC. (US) | 1990-05-03 | — | — | WO | disclosed |