Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 13/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9616583 | 0.75 | CYP19A1 (0.36) | CYP19A1 | |
| SCHEMBL9616582 | 0.69 | AR (0.36) | SHBGCYP3A4TDP1 | |
| SCHEMBL9700995 | 0.68 | CYP19A1 (0.34) | CYP19A1 | |
| SCHEMBL7997769 | 0.66 | GRIN1 (0.47) | SHBGCYP19A1 | |
| SCHEMBL9616803 | 0.65 | PGR (0.40) | SHBGCYP19A1CYP3A4CYP2C19 | |
| SCHEMBL9136957 | 0.62 | SHBG (0.52) | SHBG | |
| SCHEMBL9700988 | 0.61 | — | — | |
| SCHEMBL9616801 | 0.61 | PGR (0.36) | SHBGCYP19A1CYP3A4CYP2C19 | |
| SCHEMBL28600625 | 0.56 | SHBG (0.44) | SHBGCYP19A1CYP3A4 | |
| SCHEMBL29014610 | 0.56 | TSHR (0.40) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500899-A1 | NOVEL 15,16-SECO-19-NOR PROGESTINS. | STANFORD RES INST INT (US) | 1992-09-02 | — | — | EP | disclosed |
| WO-1992004309-A1 | NOVEL 15,16-SECO-19-NOR PROGESTINS | SRI INTERNATIONAL (US) | 1992-03-19 | — | — | WO | disclosed |