Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 3/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5308527 | 0.74 | NPC1 (0.43) | KMT2ANPC1RAB9AMAPTMGAM | |
| SCHEMBL29433775 | 0.70 | CA9 (0.47) | CA9NPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL9092910 | 0.70 | CA9 (0.47) | CA9NPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL10754154 | 0.70 | MAPT (0.39) | KMT2ANPC1RAB9AMAPTPKM | |
| SCHEMBL9626749 | 0.70 | PDE4D (0.38) | KMT2ANPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL6916096 | 0.69 | CA9 (0.50) | CA9NPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL31260274 | 0.68 | KDM4E (0.51) | KMT2AMAPTGAA | |
| SCHEMBL852444 | 0.68 | CA9 (0.52) | CA9KMT2ANPC1MAPK13MAPK12 | |
| SCHEMBL577986 | 0.66 | BCHE (0.49) | NPC1RAB9AMAPT | |
| SCHEMBL28157945 | 0.66 | PDE10A (0.40) | KMT2ANPC1RAB9AMAPTMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4013681-A | — | — | None | — | — | JP | disclosed |
| JP-H0413681-A | NOVEL PYRANOQUINOLINONE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVE AS ACTIVE COMPONENT | KODAMA KK | 1992-01-17 | — | — | JP | disclosed |