Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9626819 | 0.72 | PKM (0.39) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL9617096 | 0.70 | CA9 (0.41) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL23461782 | 0.68 | KIF11 (0.36) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL9626684 | 0.68 | PDE4D (0.41) | PDE4DHSP90AA1HPGDLMNANPC1 | |
| SCHEMBL19365882 | 0.67 | HSP90AA1 (0.52) | PDE4DHSP90AA1HPGDTP53CYP3A4 | |
| SCHEMBL29590196 | 0.67 | KDM4E (0.62) | PDE4DHPGDLMNAKDM4EMEN1 | |
| SCHEMBL4253824 | 0.65 | IDO1 (0.38) | PDE4DHSP90AA1HPGDLMNAIDO1 | |
| SCHEMBL9627709 | 0.65 | BRD4 (0.36) | LMNANPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL2486626 | 0.65 | TDP1 (0.40) | HSP90AA1TDP1CTSB | |
| SCHEMBL21087315 | 0.65 | HSP90AA1 (0.37) | PDE4DHSP90AA1HPGDLMNAIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093339-A | Anticoagulant, hypotensive, antiangina, antiasthma, antiulcer, anti-platelet activating factor | KODAMA KABUSHIKI KAISHA (JP) | 1992-03-03 | — | — | US | disclosed |