SCHEMBL9617384

SCHEMBL9617384

CO[Si](CCCNc1cccc(O)c1)(OC)OC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 1/20 0.47
MTNR1B P49286 1/20 0.47
HTR7 P34969 2/20 0.44
NLRP3 Q96P20 1/20 0.41
VSIR Q9H7M9 1/20 0.40
MAPT P10636 3/20 0.39
MEN1 O00255 2/20 0.39
NPC1 O15118 2/20 0.39
NFKB1 P19838 2/20 0.39
RAB9A P51151 2/20 0.39
NFKB2 Q00653 2/20 0.39
KMT2A Q03164 2/20 0.39
RELA Q04206 2/20 0.39
CYP1A2 P05177 3/20 0.39
ALDH1A1 P00352 2/20 0.39
HDAC6 Q9UBN7 1/20 0.39
CYP3A4 P08684 3/20 0.39
CYP2D6 P10635 2/20 0.39
CYP2C19 P33261 2/20 0.39
RET P07949 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9159346 0.85 HTR7 (0.42) MTNR1AMTNR1BHTR7NLRP3VSIR
SCHEMBL6449192 0.83 MAPT (0.61) MTNR1AMTNR1BVSIRMAPTNPC1
SCHEMBL959868 0.82 MTNR1A (0.43) MTNR1AMTNR1BMAPTMEN1NPC1
SCHEMBL6831255 0.81 MAPT (0.44) MAPTMEN1KMT2AALDH1A1HTT
SCHEMBL28828211 0.80 MAPT (0.57) MTNR1AMTNR1BMAPTNPC1RAB9A
SCHEMBL41158 0.80 MAPT (0.57) MTNR1AMTNR1BMAPTNPC1RAB9A
SCHEMBL14682409 0.79 MAPT (0.51) MAPTNPC1ALDH1A1HTT
SCHEMBL30387779 0.79 MTNR1A (0.45) MTNR1AMTNR1BMAPTKMT2AALDH1A1
SCHEMBL22393149 0.79 MAPT (0.55) MTNR1AMTNR1BMAPTNPC1RAB9A
Hydrochloric Acid SCHEMBL21813259 0.79 MAPT (0.55) MTNR1AMTNR1BMAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4231356-A None JP disclosed
US-9346951-B2 Polyalkylene carbonate resin composition SK INNOVATION CO., LTD. (KR) 2016-05-24 US disclosed
US-20150203681-A1 Polyalkylene Carbonate Resin Composition SK INNOVATION CO, LTD. (KR) 2015-07-23 US disclosed
JP-H04231356-A GLASS FIBER AND GLASS FIBER REINFORCED RESIN LAMINATE NITTO BOSEKI CO LTD 1992-08-20 JP disclosed