Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3171268 | 0.77 | MAOB (0.33) | MAOB | |
| SCHEMBL14087623 | 0.74 | APEX1 (0.39) | APEX1 | |
| SCHEMBL12262878 | 0.74 | APEX1 (0.36) | APEX1 | |
| SCHEMBL9027782 | 0.74 | MAOB (0.33) | MAOBLMNAPGRHTR1AADORA3 | |
| SCHEMBL11874455 | 0.69 | IDO1 (0.51) | LMNAAPEX1PGRMAPTMAPK1 | |
| SCHEMBL11358426 | 0.66 | MAOB (0.53) | MAOBLMNAPGRHTR1AADORA3 | |
| SCHEMBL13227495 | 0.64 | APEX1 (0.68) | LMNAAPEX1PGRMAPTMAPK1 | |
| SCHEMBL14507710 | 0.63 | DUSP3 (0.45) | MAOBMAPTPTGS1PKM | |
| SCHEMBL3186176 | 0.62 | CYP3A4 (0.35) | — | |
| SCHEMBL14407313 | 0.62 | LMNA (0.62) | MAOBLMNAPGRHTR1AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4036260-A | — | — | None | — | — | JP | disclosed |
| JP-H0436260-A | PROPENE DERIVATIVE | FUJIREBIO INC | 1992-02-06 | — | — | JP | disclosed |