SCHEMBL14507710

SCHEMBL14507710

C=CCC1=C(O)C(=O)C(C)=C(O)C1=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DUSP3 P51452 1/20 0.45
▸ MAOB P27338 2/20 0.39
▸ POLB P06746 1/20 0.33
▸ KDM4E B2RXH2 2/20 0.31
▸ GLA P06280 1/20 0.31
▸ GAA P10253 1/20 0.31
▸ MEN1 O00255 2/20 0.31
▸ KMT2A Q03164 2/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ TP53 P04637 1/20 0.31
▸ CYP3A4 P08684 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ PKM P14618 1/20 0.31
▸ CDC25A P30304 1/20 0.31
▸ CDC25B P30305 1/20 0.31
▸ RPS6KA3 P51812 1/20 0.31
▸ DHODH Q02127 1/20 0.31
▸ GLO1 Q04760 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ GPR35 Q9HC97 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3171268 0.70 MAOB (0.33) MAOB
SCHEMBL939989 0.69 APAF1 (0.54) KDM4EMEN1KMT2AALDH1A1TP53
SCHEMBL3186176 0.67 CYP3A4 (0.35) POLBCYP3A4
SCHEMBL16309126 0.67 DUSP3 (0.68) DUSP3MAOBKDM4EMEN1KMT2A
SCHEMBL10573499 0.67 MEN1 (0.30) MEN1KMT2A
SCHEMBL9027595 0.67 MEN1 (0.34) MAOBPOLBKDM4EGAAMEN1
SCHEMBL9027782 0.64 MAOB (0.33) MAOBMAPTPKMPTGS1
SCHEMBL30932112 0.63 LCK (0.47) MEN1KMT2AALDH1A1TP53CYP3A4
SCHEMBL9617442 0.63 MAOB (0.36) MAOBMAPTPKMPTGS1
SCHEMBL1097952 0.63 DUSP3 (1.00) DUSP3KDM4EMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070110726-A1 Rust disease control by Aphanocladium album and/or Beauveria brongniartii PHYTOMYCO RESEARCH CORPORATION (US) 2007-05-17 — — US disclosed
US-20070110726-A1 Rust disease control by Aphanocladium album and/or Beauveria brongniartii PHYTOMYCO RESEARCH CORPORATION (US) 2007-05-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070110726-A1 Rust disease control by Aphanocladium album and/or Beauveria brongniartii ERG28, HLA-A, GET3 DUSP3 2144/4885MAOB 2302/4885POLB 2242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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