SCHEMBL961753

SCHEMBL961753

COCCOC(=O)C1C2CC3C(OC(=O)C31)C2O

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 2/20 0.31
GLA P06280 1/20 0.31
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
NPC1 O15118 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18270266 0.96 KMT2A (0.33) KMT2AMEN1
SCHEMBL12009850 0.88 NPSR1 (0.41) KMT2AMEN1ALDH1A1HTTNPSR1
SCHEMBL12920508 0.88 KMT2A (0.35) KMT2AMEN1ALDH1A1GLAHPGD
SCHEMBL12884352 0.85 THRB (0.35) KMT2AMEN1ALDH1A1HTTNPC1
SCHEMBL963171 0.85 KMT2A (0.38) KMT2AMEN1ALDH1A1HPGDNPC1
SCHEMBL962818 0.85 KMT2A (0.34) KMT2AMEN1ALDH1A1GLAHPGD
SCHEMBL12972075 0.84 MEN1 (0.31) KMT2AMEN1
SCHEMBL12884354 0.84 TSHR (0.36) KMT2AALDH1A1HPGD
SCHEMBL18776017 0.82 POLB (0.31) KMT2AMEN1POLB
SCHEMBL13011183 0.81 MEN1 (0.30) KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7871752-B2 Lactone-containing compound, polymer, resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-01-18 US disclosed
US-20080026331-A1 Lactone-containing compound, polymer, resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. 2008-01-31 US disclosed