Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | ACR | P10323 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ESRRB | O95718 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26047442 | 0.87 | ALDH1A1 (0.53) | HRH3KMT2AMAPTALDH1A1PRSS1 | |
| SCHEMBL20008749 | 0.85 | KMT2A (0.53) | KMT2AMAPTALDH1A1PRSS1ACR | |
| SCHEMBL10956570 | 0.83 | KMT2A (0.56) | KMT2AMAPTALDH1A1PRSS1ACR | |
| Hydrochloric Acid SCHEMBL10765245 | 0.83 | ALDH1A1 (0.53) | KMT2AALDH1A1PRSS1ACRMEN1 | |
| Nitric Acid SCHEMBL6033843 | 0.81 | HRH3 (0.54) | HRH3MAPTALDH1A1SMN1; SMN2KDM4E | |
| Nitric Acid SCHEMBL7232743 | 0.81 | HRH3 (0.54) | HRH3MAPTALDH1A1SMN1; SMN2KDM4E | |
| Nitric Acid SCHEMBL7232747 | 0.81 | HRH3 (0.54) | HRH3MAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11426056 | 0.81 | KMT2A (0.54) | KMT2AMAPTALDH1A1ESR1PRSS1 | |
| SCHEMBL11308053 | 0.81 | KMT2A (0.50) | KMT2AMAPTALDH1A1PRSS1ACR | |
| SCHEMBL7328271 | 0.81 | ACR (0.58) | KMT2AMAPTALDH1A1PRSS1ACR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4041472-A | — | — | None | — | — | JP | disclosed |
| JP-H0441472-A | GUANIDINOBENZOIC ACID ESTER DERIVATIVE | SANKYO CO LTD | 1992-02-12 | — | — | JP | disclosed |